| （1.首都体育学院 运动生理教研室，北京 100088；2.三峡大学 体育学院，湖北 宜昌 443002；3.北京体育大学 运动生理教研室，北京 100084） 摘 要：雄激素促进骨骼肌蛋白质合成是通过雄激素受体作用的，高原训练时高原低氧抑制蛋白质合成，导致肌肉质量下降。综述了雄激素受体的结构，作用机理，在骨骼肌中的作用机制，低氧和运动对雄激素受体的作用，明确低氧和运动条件下雄激素受体在骨骼肌蛋白质合成中的可能作用机理。 |
YE Ming1，HE Dao-yuan2，ZENG Fan-xing3
| （1.Department of Exercise Physiology，Capital Institute of Physical Education，Beijing 100088，China；2.Department of Physical Education，China Three Gorges University，Yichang 443002，China；3.Department of Exercise Physiology，Beijing Sports University，Beijing 100084，China） Abstract: The synthesis of skeletal muscle protein boosted by androgen is carried out via the functions of androgen receptor. During training in an altiplano area, hypoxemia restrains protein synthesis, causing the deterioration of muscle quality. The authors gave an overview of the structure and functioning principle of androgen receptor, func-tioning mechanism of androgen receptor in skeletal muscle, and effects of hypoxemia and movement on androgen receptor, and specified the mechanism of the possible functioning of androgen receptor in the synthesis of skeletal muscle protein under the conditions of hypoxemia and movement. |
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