| (1.苏州大学 体育学院，江苏 苏州215021； 2.徐州师范大学 体育学院，江苏 徐州221008) 摘要：为了解耐力训练大鼠进行一次定量运动后红细胞的运动氧化应激是否降低以及是否减轻了自由基对其的影响。将60只SD大鼠随机分为不训练组（C）、每次训练20 min组（T1）和每次训练40 min组（T2），训练组在跑台上以28 m/min的速度训练6周。取样前各组又随机分为安静组和定量运动组，测试大鼠红细胞中GPX、SOD及Na+-K+-ATP酶活性和MDA含量。结果发现定量运动后，未训练大鼠SOD、GPX活性及MDA含量升高，Na+-K+-ATP酶活性下降；20 min训练大鼠SOD及Na+-K+-ATP酶活性下降，MDA含量和GPX活性升高且变化程度较未训练大鼠小；40 min训练大鼠各指标变化不大。结果提示有氧耐力运动训练能降低定量运动后红细胞的氧化应激，减轻自由基对红细胞的损伤。 关键词：红细胞； 自由基； 氧化应激； 有氧耐力训练； 大鼠 中图分类号：G8047文献标识码：A文章编号：1006-7116(2006)04-0050-03 |
LI Min1， CAO Zhifa2
| (1.School of Sports Science,Soochow University,Suzhou 215021，China； 2.School of Sports Science, Xuzhou Normal University,Xuzhou 221000，China) Abstract:In order to know about whether the kinetic oxidative stress of erythrocytes in aerobic endurance trained rats is lowered or has abated the effect of free radicals on the rats after they have done a quantified exercise,the authors divided 60 SD rats randomly into a group not trained (C),a group trained for 20 minutes each time (T1),and a group trained for 40 minutes each time (T2). The rats in the trained groups were trained for 6 weeks,running on the run track at a speed of 28m/min. Before sampled,the rats in each group was randomly divided again into a rest group and a quantified exercising group, and then the activity of GPX,SOD and enzyme Na+-K+-ATP and the content of MDA in erythrocytes in the rats were tested. The results revealed the following findings: As for the untrained rats,the activity of GPX and SOD as well as the content of MDA are heightened,while the activity of enzyme Na+-K+-ATP is lowered;as for the rats trained for 20 minutes,the activity of SOD and enzyme Na+-K+-ATP is lowered,while the content of MDA and the activity of GPX are heightened and such changes are less significant than those occurred to the untrained rats; as for the rats trained for 40 minutes,various indexes do not change much. The results indicate that aerobic endurance exercising training can lower the oxidative stress of erythrocytes after quantified exercising and abate the damage of free radicals on erythrocytes. Key words:erythrocyte; free radical; oxidative stress; aerobic endurance training; rat |
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