运动性心肌肥大的信号转导通路(综述)

(1.华南师范大学体育科学学院，广东广州　510631；2.东华理工学院体育系，江西抚州344000)

摘要：综述了近年来生理界和运动生理界关于心肌肥大的机制及其有关的信号转导途径的若干研究，初步探讨运动性心肌肥大可能存在的信号转导通路，以期有助于阐述运动性心肌肥大的细胞分子机制。

关键词：运动性心肌肥大；信号传导通路；超负荷；血管紧张素Ⅱ

中图分类号：G804.2文献标识码：A　文章编号：1006-7116(2004)04-0052-04

Signal transduction pathways in exercise induced cardiac myocyte hypertrophy(A review)
WAN Zhi-jun1，LI Duan-yang2, DENG Shu-xun1

(1College of Physical Education and Sport Science,South Chin a Normal University,Guangzhou 510631,China；
2Department of Physical Education,Donghua Engineering and Science Col lege,Fuzhou 344000,China)
Abstract: The current status of the mechanism and the signal transduct ion pathways of cardiac hypertrophy is reviewed,and the putative signal transdu ction pathways of exercise induced cardiac hypertrophy is also discussed.The aim is to facilitate the elucidation of the cellular and molecular mechanisms of ex ercise induced cardiac hypertrophy.
Key words: exercise induced myocyte hypertrophy; signal transdu ction pathways; overloaded pressure; AngⅡ

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