| (1华南师范大学 体育科学学院，广东 广州510631；2中国中医研究院西苑医院 心血管病研究室，北京100091；3北京体育大学 运动人体科学教研室，北京100084）〖HT5”H〗摘要：目的：通过观察不同剂量CLT和FT对于垂体后叶素引起的急性心肌缺血大鼠心电图的影响，探讨其抗大鼠急性心肌缺血、保护心肌的作用。方法：灌胃给药7 d，尾静脉注射垂体后叶素2次，并描记心电图。结果：第2次注射后15 min，造模组和FT组ST-T的升高超过1 mV，出现急性心肌缺血，并且心肌缺血阳性率升高；CLT小、大剂量组ST-T升高值明显降低，心肌缺血阳性率明显减少。结论：CLT有预防和减轻大鼠急性心肌缺血的作用，FT没有此作用。 关键词：急性心肌缺血；垂体后叶素；清脂片；芬氟拉明；心电图 中图分类号： G804.22；R87 文献标识码：A 文章编号：1006-7116(2002)02-0029-02 |
CUI Li-ping1，SHI Da-zhuo2, YANG Xi-rang3
| (1.Institute of Physical Education,South China Normal University, Guangzhou 510631,China；2.Academy of Traditional Chinese Medicine,Xiyuan Hospital,Beijing 100091,China；3.Teaching and Researen Section of Human Exercise Science,Beijing University of Physical Education,Beijing 100081,China) Abstract: Objective:The present study observed the effect of the different doses CLT and FT on the ECG of acute myocardial ischemia by injecting pituitrinum into tail vein in Wistar Rats. Methods: After feeding CLT and FT seven days, the rats were injected pituitrinum two times, leaded II of ECG. Results: The result revealed a significant increase of ST-T (exceed 1mV) and ischemic positive rate in 15 minutes after second injection in model group and FT group. However, it showed an obvious decrease of both two indexes in low and high dose CLT groups.Conclusion: The results indicated that CLT has the effects of preventing and treating myocardial ischemia induced by injecting pituituinum into tail vein. FT has no such the effects. Key words: acute myocardial ischemia；pituitrinum；CLT；FT；ECG |
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