运动疲劳与神经递质的生理学研究进展(综述)

(华南师范大学体育科学学院，广东广州510631)

摘要：从肌肉的外周机制和大脑中的中枢机制两个方面对运动性疲劳进行阐述，总结了神经递质与中枢疲劳的关系。资料表明，5－羟色胺（5－HT）、r－氨基丁酸（GABA）、甘氨酸（GLY）等是脑组织抑制性神经递质；而谷氨酸（GLU）和天冬氨酸（ASP）等是兴奋性神经递质。此外，多巴胺(DA)、乙酰胆碱(ACH)、血氨(NH3)等均是运动性中枢疲劳较为敏感的神经递质。

关键词：神经递质；运动疲劳；5—羟色胺；乙酰胆碱

中图分类号：G804.2 文献标识码：A 文章编号：1006-7116(2002)01-0118-03

Neurotransmitters and exercise-induced fatigue(Review)
ZHANG Lei，DENG Shu-xun

(Institute of Physical Education,South China Normal University，Guangzhou 510631,China)
Abstract: The article reveals the mechanisms of exercise-induced muscle fatigue which include the peripheral mechanism of fatigue and the central mechanism residing in the brain. It summarizes the relationship between the neurotransmitters and the central fatigue. Many evidence showed that serotonin(5-HT), gamma-aminobutyric acid(GABA), glycine (GLY) are inhibitory neurotransmitters while the glutamate(GLU) and Aspartates(ASP) are excitatory neurotransmitters. In addition to dopamine(DA)、acerylcholine(ACH)、ammonia(NH3)，et al. all of them might be neurotransmitter with a higher sensibility to central fatigue during exercise.
Key words: neurotransmitters；exercise fatigue；serotonin；acerylcholine

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