| （华南师范大学 体育科学学院，广东 广州510631） 摘要：热休克蛋白是一组结构高度保守的多肽，几乎所有生物体受到某种额外程度的应激时都有热休克蛋白的表达，因此又称为应激蛋白。热休克蛋白赋予细胞或生物体从各种应激中恢复的能力和保护他们免遭这些应激因素的伤害。其中，表现最为明显的是热耐受能力。热休克蛋白作为一种分子伴侣，能维持细胞的正常结构。热休克蛋白在抗氧化、抗细胞凋亡中也具有重要作用。运动也能诱导心肌、骨骼肌等组织中热休克蛋白的表达，并与运动方式、运动强度密切相关，在骨骼肌中的表达表现出肌纤维特异性。 关键词：热休克蛋白； 运动； 心肌； 骨骼肌； 研究进展 中图分类号：G804.2；G804.7 文献标识码：A 文章编号：1006-7116(2005)05-0123-04 |
FAN Qi-wei， XIAO Guo-qiang
| （College of Physical Education，South China Normal University，Guangzhou 510631，China） Abstract: Heat shock protein is a set of polypeptides with a highly conserved structure,and is also called heat stress protein since almost all organisms will have a heat shock protein expression when they are subject to extra stresses to a certain extent. Heat shock protein gives cells or organisms the abilities to recover from various stresses and protects them from being harmed by these stress factors. Among the abilities above, heat resisting ability has the most prominent performance. As a company of molecules, heat shock protein can maintain the normal structure of cells. Heat shock protein also plays an important role in anti-oxidation and anti-apoptosis. Heat shock protein expression in cardiac and skeletal muscles can be induced by an exercise as well, and is closely related to the form and intensity of the exercise. Heat shock protein expression in skeletal muscle shows in distinctive muscle fibers. Key words: heat shock protein; exercises; cardiac muscle; skeletal muscle; progress of research |
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