| (陕西师范大学 体育学院暨运动生物学研究所，陕西 西安 710062) 摘要：通过抗疲劳相关检测指标的测试，研究芦荟对小鼠自由基代谢和抗疲劳效果的影响。用运动训练和建立动物训练模型，测试小鼠血液中乳酸脱氢酶（LDH）活性及血尿素氮（BUN）浓度、血糖（Gluc）浓度、血红蛋白（Hb）质量浓度与肾组织超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）活性、总抗氧化能力（TAC）和丙二醛（MDA）质量摩尔浓度。结果：安静时芦荟组小鼠Hb质量浓度和肾组织SOD、GSH-Px活性、TAC高于安静对照组，而血液LDH活性、BUN、Gluc浓度和肾组织MDA质量摩尔浓度低于对照组，其中TAC、 GSH-Px活性和Gluc浓度、MDA质量摩尔浓度差异显著（〖WT5”BX〗P<0.05〖WT5”BZ〗）；运动后即刻芦荟组小鼠血液中Hb质量浓度、Gluc浓度和肾组织SOD、GSH-Px活性、总抗氧化能力均显著高于对照组（〖WT5”BX〗P〖WT5”BZ〗<0.05），而血液LDH活性、BUN浓度和组织MDA质量摩尔浓度明显低于对照组（〖WT5”BX〗P〖WT5”BZ〗<0.05）；运动后24 h恢复组各指标均趋于安静时水平，而除SOD活性和BUN浓度与对照组比较无显著差异外（〖WT5”BX〗P〖WT5”BZ〗>0.05），LDH活性、Hb质量浓度、Gluc浓度、 GSH-Px、TAC活性和MDA质量摩尔浓度均有显著差异（〖WT5”BX〗P〖WT5”BZ〗<0.05）。芦荟具有明显的抗疲劳、抗氧化效果，对小鼠运动性肾损伤有明显的保护作用，可作为抗疲劳功能食品进行开发和研究。 关键词：库拉索芦荟；抗疲劳功能食品；自由基；肾脏；小鼠 中图分类号：G872.7 文献标识码：A 文章编号：1006-7116(2003)02-0050-03 |
TANG Liang， XIONG Zheng-ying
| (Institute of Physical Education and Sports Biology, Shaanxi Normal University, Xi'an 710062,China) Abstract:Objective：To study the effects of Aloe on metabolism of free radical and anti-fatigue.Methods:By building the model of trained mice, the targets of LDH, BUN, Gluc, Hb in the bloods and the activities of SOD,GSH-Px,total antioxidation capacity(TAC) and concentration of MDA were tested in the kidney of trained mice. Results: The activities of Hb,SOD,GSH-Px, and TAC of Aloe group were higher and LDH, BUN, Gluc, MDA concentrations were lower than those of control group in rest state, which Gluc, TAC and MDA have obviously differences (P<0.05).In immediately after exhaustive exercise, the blood's Gluc, Hb and kidney's SOD ,GSH-Px activities and TAC are obvious higher and LDH, BUN,MDA concentration are remarkable lower in Aloe groups than those in control groups. After 24-hour recovery, except SOD and BUN,the others targets have significant difference compared Aloe group with its control group (P<0.05).Conclusion: Aloe could increase the capacity of antioxidation and anti-fatigue and reduce the damage of the tissue caused by exercise. Aloecould be studied and exploited as an anti-fatigue activity substance. Key words: Aloe veres L.;anti-fatigue activity substance;free radical; kidney; mice |
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