运动性与病理性心肌肥厚对比研究进展(综述)

（1华东师范大学体育与健康学院，上海200062； 2.上海体育学院研究生部，上海200438）

摘要：综合分析了分子生物学上的研究成果，说明：（1）Ca2+是介导心肌细胞肥大的中心环节；（2）心肌成纤维细胞的增殖及其旁(自)分泌功能可能是决定肥厚心肌架构的重要因素，从而揭示运动性心肌肥厚与高血压性心肌肥厚在心脏机能上的差异可能与心肌架构密切相关。

关键词：高血压；心肌肥厚；钙离子；心肌架构

中图分类号：R542.2 文献标识码：A 文章编号：1006-7116(2002)03-0041-03

Review on comparative study between exercise-induced and pathological myocardial hypertrophy
QI Zhen-tang1，PANG Jin2，XU Haowen1

(1.Institute of PE and Health,East China Normal University，Shanhai 200062,China;2.Graduate Department,Shanhai Institute of Physical Education,Shaihai 200438,China)

Abstract: After sumarizing a lot of data from molecular biology, the following inference has arrived: (1) Ca2+is the central moment in the process of myocardial hypertrophy. (2) the multiplication and secretion of myocardial fibrocyte are important factors influencing the structure of myocardial tissue，exerciseinduced myocardial hypertrophy is different from pathological myocardial hypertrophy in the structure of myocardial tissue.
Key words: hypertension； myocardial hypertrophy；Ca2+；structure of myocardial tissue

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